Leukeran 5 mg

Generic Name: Chlorambucil

Leukeran is used for treating certain cancers. It may also be used to treat other conditions as determined by your doctor.
Leukeran is an alkylating agent. It works by binding to the RNA or DNA of certain cancer cells, which helps to slow down their growth and reproduction.
Leukeran is a medication used to treat several kinds of cancer and other conditions including Hodgkin's disease (a type of lymphoma), malignant lymphoma (including lymphosarcoma), clasmocytoma, chronic lymphocytic leukemia, giant follicular lymphoma, hairy cell leukemia (a sub-type of chronic lymphoid leukemia), myeloma, ovarian cancer, breast cancer, Letterer-Siwe disease (genetically stipulated proliferation of histiocytes), chorionepithelioma of the uterus, glomerular nephritis,  dermatomyositis, rheumatoid arthritis, sarcoidosis, uveitis, nephrotic syndrome. Leukeran's active substance is chlorambucil, a bifunctional alkylating agent.

Precautions
Carefulness should be exercised in the patients with inhibited bone marrow function (expressed as leukopenia, thrombocytopenia, and anemia, including ones associated with a malignant process and on the background of the previous radiotherapy or chemotherapy), severe liver disease and kidney failure, acute gastrointestinal disease, in pregnant and breastfeeding women. Blood cell count,leukocytes count, platelets count, and Hb examination should be performed at least once weekly.

Contraindications
Leukeran cannot be used in the patients with hypersensitivity to its components (including other alkylating agents).

Possible Side Effects
The most common side effects are nausea, vomiting, changes in menstrual period. Contact your doctor immediately if you have following adverse reactions: painful or difficult urination, fever, chills, black, tarry or bloody stools, easy bruising or bleeding, blood in urine, swollen extremities, sores in mouth or on lips, small red spots on the skin, jaundice, cough, lower back or side pain, joint pain, abdominal pain, confusion, hallucinations, muscle twitching, agitation, trouble walking, weakness, paralysis.